Jan. 23, 2026 PC

S.E.M.I.: Side Effects May Include...

Game facts

When is S.E.M.I.: Side Effects May Include... coming out?

S.E.M.I.: Side Effects May Include... is scheduled to release on Jan 23, 2026.

What are the S.E.M.I.: Side Effects May Include... review scores?

There is no published OpenCritic score for S.E.M.I.: Side Effects May Include... yet.

Which platforms is S.E.M.I.: Side Effects May Include... on?

S.E.M.I.: Side Effects May Include... is listed on PC (Microsoft Windows).

S.E.M.I. is a cooperative online game about escaping from a special clinic. Here you and up to 3 of your feeble-minded loyal friends in the role of patients fight with the staff and other patients and find yourself in unexpected situations. Teamwork is essential, as randomized events and experimental drugs will lead your party into unpredictable mayhem. Pop pills with your friends as you cooperate to gain your freedom.

Hack and slash/Beat 'em up
Indie
Arcade
Single player
Multiplayer
Co-operative
Screenshots
Storyline

S.E.M.I. is a cooperative online game about escaping from a special clinic. Here you and up to 3 of your feeble-minded loyal friends in the role of patients fight with the staff and other patients and find yourself in unexpected situations. Teamwork is essential, as randomized events and experimental drugs will lead your party into unpredictable mayhem. Pop pills with your friends as you cooperate to gain your freedom.

Artworks
S.E.M.I.: Side Effects May Include... artwork
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